Mitochondriopathy: skeletal and heart muscle biopsy | EM

Test Details A variety of clinical EM services are offered by the Electron Microscopy Facility which includes preparation of one micron thick toluidine blue stained plastic sections and ultrathin sections in anticipation of routine transmission electron microscopy. Digital images and expert diagnostic interpretation are provided by members of the Divisions of Anatomic and Molecular Pathology and Neuropathology in the Department of Pathology and Immunology.
Methodology Electron microscopy
Performed Monday – Friday
Turnaround 2 – 3 business days
Sample Collection Excise tissue in 1mmx1mm or less in 1 dimension. Use modified Karnovsky’s fixative in a 30:1 fixative to tissue ratio, contact lab directly for fixative information.
Minimum sample volume Maximum 1mm x 1mm in one dimension for whole tissue
Storage/Transport Conditions Room temperature in EM fixative
Unacceptable Conditions Wrong Fixative, delay after excision, tissue too large to penetrate
Special Instructions Always contact lab for sample preparation instructions and guidance prior to sample collection
CPT Code(s) 88348