Cancer chromosome analysis | Classical cytogenetics

Test Details Detects aneuploidy, rearrangements, deletions, inversions
Methodology Chromosome analysis / karyotype
Performed Monday – Saturday
Turnaround 14 – 21 days
Specimen Requirements Bone core, bone marrow aspirate, lymph node, peripheral blood, solid tumor, tissue biopsy
Sample Collection Hematologic specimens: Collect 1-2 mL bone marrow; 5-10 mL blood; 0.5-1 cm2 biopsy (bone core; lymph node). Collect bone marrow or blood in a sodium heparin (green-top) Vacutainer. Invert tube immediately upon completion of blood collection to prevent formation of clots. For bone marrow it is important that a first draw, spicule-rich sample be collected. Solid tumors/neoplastic tissue: Collect 3-4 mm2 biopsy (about the size of a pencil eraser) in a sterile, screw-top container filled with transport media (provided by cytogenetics lab). Ensure the container is tightly sealed to prevent leakage.
Storage/Transport Conditions Room temperature
Unacceptable Conditions
Special Instructions Refrigerate if sample cannot be delivered within 24 hours; Send to Rapid Response or SLCH Central Receiving
CPT Code(s)